Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions
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- 作者：Huan Hea ; b ; Dan Liub ; c ; Hui Lina ; b ; Shanshan Jianga ; b ; c ; Ying Yinga ; b ; d ; Shao Chunb ; Haiteng Denge ; Joseph Zaiab ; Rong Wenf ; Zhijun Luob ; d ; zluo@bu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Act ; protein kinase B ; DMEM ; Dulbecco's modified Eagle's medium ; EGF ; epidermal growth factor ; ERK ; extracellular signal regulated kinase ; FBS ; fetal bovine serum ; GFP ; green fluorescent protein ; Her2 ; human epidermal growth factor receptor 2 ; HMGB1 ; high mobility group box 1 ; JNK ; c-Jun N-terminal kinase ; MEK1 ; mitogen and extracellular signal activated kinase (mitogen activated kinase kinase) ; MET ; hepatocyte growth factor receptor ; NFκB ; nuclear factor kappa B ; PEBP ; phosphatidylethanolamine
- 刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：1863
- 期：7
- 页码：1682-1689
- 全文大小：1047 K
文摘
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PEBP4 is a secreted and glycosylated protein.
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The carboxyterminal conserved sequence contributes to the secretion.
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PEBP4 does not participate in ERK activation by EGF.
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PEBP4 is required for Akt activation.