The Serotonergic System Tracks the Outcomes of Actions to Mediate Short-Term Motor Learning
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- 作者：Takashi Kawashima1 ; Maarten F. Zwart1 ; Chao-Tsung Yang1 ; Brett D. Mensh1 ; Misha B. Ahrens1 ; 2 ; ahrensm@janelia.hhmi.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：motor learning ; short-term memory ; imaging ; dorsal raphe nucleus ; serotonin ; serotonergic system ; neural circuits ; zebrafish ; neuromodulation ; neuroscience
- 刊名：Cell
- 出版年：2016
- 出版时间：3 November 2016
- 年：2016
- 卷：167
- 期：4
- 页码：933-946.e20
- 全文大小：8785 K
文摘
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The dorsal raphe nucleus (DRN) mediates short-term locomotor learning
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DRN responses convey the visual outcomes of swim motor commands
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Learning induces a motor memory signal in the DRN that modulates future swimming
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DRN ablation/activation abolishes/extends the effect of learning