Identification and quantification of novel cranberry-derived plasma and urinary (poly)phenols
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- 作者：Rodrigo P. Felicianoa ; Albert Boeresa ; Luca Massacessia ; b ; Geoffrey Istasa ; M. Rita Venturac ; Clá ; udia Nunes dos Santosc ; d ; Christian Heissa ; Ana Rodriguez-Mateosa ; ana.rodriguez-mateos@med.uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cranberry ; (Poly)phenols ; Bioavailability ; Absorption ; Metabolism ; Excretion
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：599
- 期：Complete
- 页码：31-41
- 全文大小：1713 K
文摘
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We investigated the absorption, metabolism and excretion of (poly)phenols in plasma and urine of healthy men after consumption of cranberry juice.
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A total of 60 cranberry-derived phenolic metabolites were identified using UPLC-Q-TOF-MS analysis with authentic standards, including 43 novel metabolites.
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We provide evidence that cranberry (poly)phenol absorption and metabolism is more complex than previously thought.
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Our extensive description of the bioavailability of cranberry (poly)phenols lays important ground work to understand their metabolic fate.