High vancomycin MICs within the susceptible range in Staphylococcus aureus bacteraemia isolates are associated with increased cell wall thickness and reduced intracellular killing by human phagocytes
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- 作者：Rocí ; o Falcó ; na ; 1 ; Alba Martí ; nezb ; 1 ; Eliseo Alberta ; Silvia Madrida ; Rosa Oltrac ; Estela Gimé ; neza ; Mario Sorianod ; Ví ; ctor Vinuesaa ; Daniel Gozalbob ; Marí ; a Luisa Gile ; David Navarroa ; f ; david.navarro@uv.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Vancomycin ; Minimum inhibitory concentration (MIC) ; Staphylococcus aureus ; Intracellular killing ; Cell wall thickness ; Human phagocytes
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：47
- 期：5
- 页码：343-350
- 全文大小：1782 K
文摘
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Staphylococcus aureus susceptibility to killing by phagocytes varies between isolates.
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S. aureus vancomycin MICs inversely correlate with susceptibility to killing.
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S. aureus cell wall thickness inversely correlates with susceptibility to killing.