Expression pattern of invasion-related molecules in the peritumoral brain
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- 作者：Á ; lmos Kleknera ; 1 ; neurosurgery.debrecen@freemail.hu" class="auth_mail" title="E-mail the corresponding author ; Gá ; bor Hutó ; czkia ; 1 ; Jó ; zsef Virgaa ; Judit Remé ; nyi-Puská ; ra ; Judit Tó ; thb ; Beá ; ta Scholtzc ; É ; va Csőszc ; Gergő Kalló ; c ; Lá ; szló ; Steinerc ; Tibor Hortobá ; gyid ; Lá ; szló ; Bogná ; ra
- 关键词：Glioblastoma ; Brain metastasis ; Invasion ; Extracellular matrix ; Gene expression ; Peritumoral brain
- 刊名：Clinical Neurology and Neurosurgery
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：139
- 期：Complete
- 页码：138-143
- 全文大小：1454 K
文摘
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Gene and protein levels of ECM molecules in human brain samples were examined.
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Differences in the peritumoral and normal tissues were revealed.
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We could identify molecules that may affect the peritumoral invasion processes.
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ECM of peri-glioblastoma does not react definitely to the spreading of the tumour.
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Peri-metastatic ECM changes can probably decrease tumour infiltration.