AMPKα1 overexpression alleviates the hepatocyte model of nonalcoholic fatty liver disease via inactivating p38MAPK pathway
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- 作者：Hong-Ai Zhanga ; b ; Xiao-Yan Yangc ; Yan-Feng Xiaoa ; yanfengxiaocn@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：NAFLD ; AMPKα1 ; Metabolism ; Inflammatory cytokines ; p38MAPK
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：27 May 2016
- 年：2016
- 卷：474
- 期：2
- 页码：364-370
- 全文大小：1863 K
文摘
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AMPKα1 overexpression suppresses lipid accumulation in the cytoplasm in a steatotic hepatocyte model.
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AMPKα1 overexpression maintains the survival of steatotic hepatocyte model.
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AMPKα1 overexpression sustains the metabolism homeostasis in the steatotic hepatocyte model.
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AMPKα1 overexpression alleviates the inflammatory response and inhibits the activation of p38MAPK.