The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory
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- 作者：Mary Muhia1 ; 6 ; Edda Thies1 ; 6 ; Dorthe Labonté ; 1 ; Amy E. Ghiretti5 ; Kira V. Gromova1 ; Francesca Xompero2 ; Corinna Lappe-Siefke1 ; Irm Hermans-Borgmeyer3 ; Dietmar Kuhl2 ; Michaela Schweizer4 ; Ora Ohana2 ; Jü ; rgen R. Schwarz1 ; Erika L.F. Holzbaur5 ; Matthias Kneussel1 ; matthias.kneussel@zmnh.uni-hamburg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：neuron ; dendrite ; microtubule dynamics ; kinesin ; KIF21B ; LTP ; spine ; synapse ; learning and memory
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：3 May 2016
- 年：2016
- 卷：15
- 期：5
- 页码：968-977
- 全文大小：3767 K
文摘
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KIF21B is a processive kinesin that regulates microtubule dynamics
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KIF21B depletion alters neuronal dendritic tree branching and spine formation
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