Auraptene induces oligodendrocyte lineage precursor cells in a cuprizone-induced animal model of demyelination
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- 作者：Mitsunari Nakajima ; mnakajim@cc.matsuyama-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Risei Shimizu ; Kohei Furuta ; Mami Sugino ; Takashi Watanabe ; Rui Aoki ; Satoshi Okuyama ; Yoshiko Furukawa
- 关键词：CC ; corpus callosum ; GFAP ; glial fibrillary acidic protein ; Iba-1 ; ionized calcium-binding adaptor molecule 1 ; MS ; multiple sclerosis ; olig2 ; oligodendrocyte transcription factor 2 ; OPCs ; oligodendrocyte precursor cells ; PBS(&minus ; ) ; magnesium and calcium-free phosphate-buffered saline ; PLP ; proteolipid protein ; MBP ; myelin-basic protein ; PDGFR-α ; platelet derived-growth factor receptor-α
- 刊名：Brain Research
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：1639
- 期：Complete
- 页码：28-37
- 全文大小：2489 K
文摘
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Auraptene did not affect MBP expression reduced by cuprizone.
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Auraptene did not affect PDGFR-alpha expression increased by cuprizone.
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Auraptene enhanced olig2 expression increased by cuprizone.
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Auraptene reduced microglial activation induced by cuprizone.