Wheat bran feruloyl oligosaccharides ameliorate AAPH-induced oxidative stress in HepG2 cells via Nrf2 signalling
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- 作者：Huijuan Zhanga ; Jing Wanga ; b ; c ; wangjing@th.btbu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Yingli Liua ; Lingxiao Gonga ; Baoguo Suna
- 关键词：Feruloyl oligosaccharides (FOs) ; Nrf2 ; AAPH ; HepG2
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：25
- 期：Complete
- 页码：333-340
- 全文大小：734 K
文摘
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Wheat bran feruloyl oligosaccharides (FOs) had protective effects against AAPH-induced oxidative stress in HepG2 cells.
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FOs increased the activities and mRNA expression levels of phase II detoxifying/antioxidant enzymes, such as SOD, CAT, and GPx.
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FOs simultaneously increased the protein expression levels of SOD, CAT, GPx, and Nrf2.