Fatal Clostridium tertium septicemia in a nonneutropenic patient

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• 作者：Dennis Tappe ; Jü ; rgen Dirks ; Rainer Mü ; ller ; Jö ; rg Brederlau ; Marianne Abele-Horn ; Sebastian Suerbaum ; Oliver Kurzai
• 关键词：Clostridium tertium septicemia ; Ileus ; Nonneutropenic patient ; Broad-spectrum cephalosporins
• 刊名：Journal of Infection
• 出版年：2005
• 出版时间：January 2005
• 年：2005
• 卷：50
• 期：1
• 页码：76-80
• 全文大小：180 K

文摘

Clostridium tertium septicemia is a rare condition that predominantly occurs in neutropenic patients with concomitant abdominal disease. We report the fatal case of a nonneutropenic, 51-year-old patient with mechanical ileus and post-operative C. tertium septicemia, resulting in widespread pathology with multi-organ failure. As C. tertium is aerotolerant, often gram-variable and mostly resistant to broad-spectrum cephalosporins, differentiation is difficult and empirical therapeutic strategies may fail.