Sensitization of Eu(III) luminescence by donor-phenylethynyl-functionalized DTPA and DO3A macrocycles

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• 作者：Anthony D’ ; Alé ; o ; Mustapha Allali ; Alex ; re Picot ; Patrice L. Baldeck ; Loï ; c Toupet ; Chantal Andraud ; Olivier Maury
• 关键词：Luminescence ; Spectroscopy ; Macrocyclic ligand ; Nonlinear optics ; Two-photon absorption
• 刊名：Comptes Rendus Chimie
• 出版年：2010
• 出版时间：June-July 2010
• 年：2010
• 卷：13
• 期：6-7
• 页码：681-690
• 全文大小：755 K

文摘

The synthesis and complexation to Eu(III) of two macrocyclic ligands functionalized donor-phenylethynyl-moieties as sensitizer is presented. The two ligands based on DTPA bis-amide ([Eu(L¹)]) and DO3A ([Na][Eu(L²)]) have been chosen because of their increased stability in water for potential applications as luminescent bioprobes for one- or two-photon excited scanning microscopy. The DTPA and DO3A ligands possess oxygen or sulfur donor atoms, respectively, connected to a triethyleneglycol (PEG) chain to ensure the water solubility. The optical properties were studied and reveal that ([Eu(L¹)]) present a lower brightness than the ([Na][Eu(L²)]) counterpart because of its inner sphere water molecule coordination that quenches the emission. On the other hand, [Na][Eu(L²)] exhibits excellent spectroscopic properties with high quantum yield  = 0.284, and brightness B = 10,220 M⁻¹cm⁻¹(defined as .). Unfortunately, the two-photon cross-section of this last complex was measured to be only 4 GM limiting its potential applications to linear microscopy.