Pertussis specific cell-mediated immune responses ten years after acellular pertussis booster vaccination in young adults
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- 作者：Kirsi Grö ; ndahl-Yli-Hannukselaa ; b ; kagron@utu.fi" class="auth_mail" title="E-mail the corresponding author ; Leni Kaukob ; leni.mannermaa@utu.fi" class="auth_mail" title="E-mail the corresponding author ; Olivier Van Der Meerenc ; Olivier.x.van-der-meeren@gsk.com" class="auth_mail" title="E-mail the corresponding author ; Jussi Mertsolad ; jussi.mertsola@utu.fi" class="auth_mail" title="E-mail the corresponding author ; Qiushui Hea ; b ; e ; qiushui.he@utu.fi" class="auth_mail" title="E-mail the corresponding author
- 关键词：Acellular pertussis vaccine ; Cell-mediated immunity ; Antibodies ; Cytokines
- 刊名：Vaccine
- 出版年：2016
- 出版时间：12 January 2016
- 年：2016
- 卷：34
- 期：3
- 页码：341-349
- 全文大小：836 K
文摘
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Immunity after acellular pertussis (aP) vaccine wanes fast.
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Cell-mediated immunity was detected ten years after the last aP vaccination.
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Booster vaccine enhanced cell-mediated immunity in young adults.
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Cytokine production seems to be downregulated after booster vaccine.