Contribution of pharmaceuticals, fecal bacteria and endotoxin to the inflammatory responses to inland waters
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- 作者：Ahmed El Marghania ; 1 ; 2 ; Ajay Pradhana ; 2 ; Asmerom Seyouma ; Hazem Khalafa ; Torbjö ; n Rosb ; Lars-Hå ; kan Forsbergc ; Tomas Nermarkd ; Lisa Ostermane ; Ulf Wiklundf ; Per Ivarssong ; Jana Jassa ; jana.jass@oru.se" class="auth_mail ; Per-Erik Olssona ; per-erik.olsson@oru.se" class="auth_mail
- 关键词：Wastewater treatment plants ; Immune response ; Cytokines ; Bacteria ; Inflammation ; Pharmaceuticals
- 刊名：Science of the Total Environment
- 出版年：1 August 2014
- 年：2014
- 卷：488-489
- 期：Complete
- 页码：228-235
- 全文大小：450 K
文摘
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The present study was performed to determine the distribution of pro-inflammatory effects to inland waters.
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Three different wastewater treatment plants and their recipient lakes were studied.
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The levels of pharmaceuticals in the WWTPs and lakes were determined and compared to the immune response elicited by urinary bladder and immune cells.
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The results of the present study indicate that the cytokine profiles of exposed cells correlate to the endotoxin load of the waters rather than to the levels of pharmaceuticals or live bacteria load.