Voltammetric detection of the S100B protein using His-tagged RAGE domain immobilized onto a gold electrode modified with a dipyrromethene-Cu(II) complex and different diluents
详细信息 查看全文
- 作者：Katarzyna Kurzątkowskaa ; Agata Jankowskaa ; Aleksandra Wysłouch-Cieszyńskab ; Liliya Zhukovab ; Monika Puchalskab ; Wim Dehaenc ; Hanna Radeckaa ; Jerzy Radeckia ; j.radecki@pan.olsztyn.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：S100B protein ; His-tagged RAGE receptor ; Alzheimer's disease ; Dipyrromethene&ndash ; Cu(II) complex ; Electrochemical biosensors
- 刊名：Journal of Electroanalytical Chemistry
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：767
- 期：Complete
- 页码：76-83
- 全文大小：696 K
文摘
- •
Dipyrromethene–Cu(II) complex was suitable for oriented immobilization of His6–RAGE domains.
- •
Dipyrromethene–Cu(II) complex was a good transducer of RAGE–S100B recognition process.
- •
Presence of different diluents has significant influence on SAM properties.
- •
Biosensors have good detection limits in pM range recorded in human plasma.