Risk Factors and Utility of a Risk-Based Algorithm for Monitoring Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections in Pediatric Recipients after Allogeneic Hematopoietic Cell Transplantation
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- 作者：Evelyn Rustia1 ; Leah Violago2 ; Zhezhen Jin3 ; Marc D. Foca1 ; Justine M. Kahn1 ; Staci Arnold4 ; Jean Sosna1 ; Monica Bhatia1 ; Andrew L. Kung1 ; Diane George1 ; James H. Garvin1 ; Prakash Satwani1 ; ps2087@columbia.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Viral infections ; Pediatrics ; Bone marrow transplantation
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：22
- 期：9
- 页码：1646-1653
- 全文大小：654 K
文摘
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Pretransplantation viremia, cytomegalovirus risk status, and use of alemtuzumab are associated with post–allogeneic hematopoietic cell transplantation viremia
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Cytomegalovirus risk status, viremia, and viral disease result in higher health care utilization
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The algorithm developed from our data can potentially reduce viral PCR testing by 50%
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Preventative treatment strategies for children at risk of post–allogeneic hematopoietic cell transplantation viremia are needed