Requirement of TLR4 signaling for the induction of a Th1 immune response elicited by oligomannose-coated liposomes
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- 作者：Yuko Matsuokaa ; Hideaki Takagib ; Minami Yamatania ; Yasuhiro Kurodaa ; Katsuaki Satob ; Naoya Kojimaa ; naoyaki@keyaki.cc.u-tokai.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：CLR ; C-type lectin receptor ; DPPC ; dipalmitoylphosphatidylcholine ; DPPE ; dipalmitoylphosphatidylethanolamine ; Man3 ; mannotriose ; Man3-DPPE ; neoglycolipids constructed with mannotriose and dipalmitoylphosphatidylethanolamine ; OML ; oligomannose-coated liposome
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：178
- 期：Complete
- 页码：61-67
- 全文大小：1071 K
文摘
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TLR4 signaling is essential for induction of Th1 immune response elicited by OMLs.
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TLR4 signaling is not involved in cell maturation and activation following OML uptake.
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TLR4 signaling elicited with OML uptake is required for cell migration.