The third to fifth zinc fingers play an essential role in the binding of ZFP809 to the MLV-derived PBS
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- 作者：Yu Ichida ; ichida-y@ncchd.go.jp" class="auth_mail" title="E-mail the corresponding author ; Yuko Utsunomiya ; Masafumi Onodera
- 关键词：Retroviral vector ; Kruppel-associated box-containing zinc finger proteins (KRAB-ZFPs) ; Zinc finger protein 809 (ZFP809)
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：15 January 2016
- 年：2016
- 卷：469
- 期：3
- 页码：490-494
- 全文大小：1072 K
文摘
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We constructed truncated and mutated ZFP809 zinc finger sequences.
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The third to fifth zinc fingers of ZFP809 are required for binding to the MLV PBS.
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Zinc fingers other than the third to fifth zinc fingers may contribute to stable protein expression.