The expression patterns of all members of the fibroblast growth factor family during early mouse tongue formation were examined.
The transcript level of each FGF was analyzed by qRT-PCR and the expression was localized by in situ hybridization.
Fgf1, Fgf2, Fgf5, Fgf6, Fgf7, Fgf9, Fgf10, Fgf13, Fgf15, Fgf16 and Fgf18 were expressed in tongue mesenchyme.
Fgf1 and Fgf2 were detected in tongue epithelium during the period between E11.5 and E14.5.