Serum antibody response to Moraxella catarrhalis proteins OMP CD, OppA, Msp22, Hag, and PilA2 after nasopharyngeal colonization and acute otitis media in children
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- 作者：Dabin Rena ; dabin.ren@rochesterregional.org" class="auth_mail" title="E-mail the corresponding author ; Anthony L. Almudevarb ; Timothy F. Murphyc ; Eric R. Lafontained ; Anthony A. Campagnarie ; Nicole Luke-Marshalle ; Janet R. Caseyf ; Michael E. Pichicheroa
- 关键词：Mcat ; Moraxella catarrhalis ; AOM ; acute otitis media ; NP ; nasopharyngeal ; OP ; oropharyngeal ; OMP ; outer membrane protein ; Spn ; Streptococcus pneumoniae ; NTHi ; non-typeable Haemophilus influenzae ; OppA ; oligopeptide permease A ; Msp ; Moraxella surface protein ; MID ; Moraxella IgD-binding protein ; Hag ; hemagglutinin ; PilA2 ; PilA clade 2 ; mo ; months ; MEF ; middle ear fluid ; E. coli ; Escherichia coli ; ELISA ; enzyme-linked immunosorbent assay ; FBS ; fetal bovine serum ; ICH ; International Conference on Ha
- 刊名：Vaccine
- 出版年：2015
- 出版时间：26 October 2015
- 年：2015
- 卷：33
- 期：43
- 页码：5809-5814
- 全文大小：469 K
文摘
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Natural serum antibody to the Mcat proteins increased with age in young children.
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High antibody levels to OppA, Msp22, and Hag correlated with reduced carriage.
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AOM events had no correlation with antibody response to most Mcat proteins tested.