Allergic fungal rhinosinusitis infiltrating anterior skull base and clivus

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• 作者：Giuseppe Meccariello^a ; Alberto Deganello^a ; Giuditta Mannelli^a ; Giacomo Bianco^a ; Franco Ammannati^b ; Christos Georgalas^c ; Oreste Gallo^a ; ^{o.gallo@med.unifi.it}
• 关键词：AFRS ; Bone erosion ; Skull base ; Clivus ; Eosinophil ; Rhinosinusitis
• 刊名：Auris Nasus Larynx
• 出版年：2013
• 出版时间：August, 2013
• 年：2013
• 卷：40
• 期：4
• 页码：405-408
• 全文大小：1856 K

文摘

Bone erosion and skull base invasion are often suggestive of a malignant mass in paranasal and nasal cavities. Nevertheless, forms of chronic rhinosinusitis, such as allergic fungal rhinosinusitis (AFRS), could mimic malignant features. Here, we report AFRS patient with orbital, anterior cranial fossa, Turkish saddle and clivus erosion. A 48-year-old Caucasian female with history of drug-resistant headache, nasal obstruction and anosmia was referred to our institution. Imaging showed hyperdense featureless tissue with signs of medial orbital wall, cribiform lamina and clivus erosions and encasement of right internal carotid artery. Massive amounts of thick and grayish mucoid material were evacuated during surgery. In case of bony erosion, malignancy should always be excluded. Often the correct diagnosis will be obtained only by operative specimens. AFRS could usually be managed endoscopically. Appropriate medical management of the AFRS should be administered in order to prevent relapses.