Trophoblast JEG-3 cells B-esterase kinetic parameters and sensitivity to inhibitors
Acetylcholinesterase and carboxylesterase (1 and 2 isoforms) are expressed.
Azinphos-methyl and chlorpyrifos insecticides differentially inhibit B-esterase.
Azinphos-methyl impacts carboxylesterase 2 and chlorpyrifos impacts carboxylesterase 1.
Trophoblasts participate in xenobiotic bioactivation/detoxification.