Dissolution behaviour of ferric pyrophosphate and its mixtures with soluble pyrophosphates: Potential strategy for increasing iron bioavailability
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Excess of pyrophosphate ions strongly increases the solubility of ferric pyrophosphate at pH 5–8.5.

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The increase in solubility is attributed to formation of soluble complexes between Fe (III) and pyrophosphate ions.

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The ~10 fold increase in the concentration of ionic iron at pH 7–8.5, which is close to the one of the small intestine, is expected to be beneficial for enhancing iron bioavailability.

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