The prevalence and risk factors associated with osteoradionecrosis of the jaw in oral and oropharyngeal cancer patients treated with intensity-modulated radiation therapy (IMRT): The Memorial Sloan Kettering Cancer Center experience

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• 作者：Adepitan A. Owosho^a (B.Ch.D) ; C. Jillian Tsai^b (MDPhD) ; Ryan S. Lee^c (DDS) ; Haley Freymiller^a (DMD) ; Arvin Kadempour^a (DDS) ; Spyridon Varthis^a (DDS) ; Adi Z. Sax^a (BS) ; Evan B. Rosen^a (DDSMPH) ; SaeHee K. Yom^a (DDSMPH) ; Joseph Randazzo^a (DDS) ; Esther Drill^d (MS) ; Elyn Riedel^d (MS) ; Snehal Patel^e (MD) ; Nancy Y. Lee^b (MD) ; Joseph M. Huryn^a (DDS) ; Cherry L. Estilo^a ; ^{estiloc@mskcc.org} (DMD)
• 关键词：Osteoradionecrosis ; Intensity-modulated radiation therapy ; Oral cancer ; Oropharyngeal cancer ; Head and neck cancer ; Prevalence ; Risk factors
• 刊名：Oral Oncology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：64
• 期：Complete
• 页码：44-51
• 全文大小：892 K
• 卷排序：64

文摘

The prevalence of ORN in OCC & OPC patients treated with IMRT is 4.3%. OPC patients are prone to develop ORN earlier compared to OCC patients. High radiation dose, poor periodontal status and alcohol use are associated with ORN.