Neoplastic extracellular matrix environment promotes cancer invasion in vitro
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- 作者：Elias Sundquista ; b ; elias.sundquist@oulu.fi" class="auth_mail" title="E-mail the corresponding author ; Outi Renkoc ; 1 ; Sirpa Saloa ; b ; d ; Johanna Maggac ; Nilva K. Cervignee ; Pia Nyberga ; b ; f ; Juha Ristelia ; g ; h ; Raija Sormuneni ; j ; Olli Vuolteenahok ; Flá ; via Zandonadil ; Adriana F. Paes Lemel ; Ricardo D. Colettae ; Heikki Ruskoahoc ; m ; Tuula Saloa ; b ; n
- 关键词：CAF ; carcinoma-associated fibroblast ; CHX ; chlorhexidine ; ECM ; extracellular matrix ; EMT ; epithelial-mesenchymal transition ; FGF ; fibroblast growth factor ; HGF ; hepatocyte growth factor ; ICTP ; carboxy-terminal peptide of type I collagen ; IIICTP ; carboxy-terminal peptide of type III collagen ; LFQ ; label-free quantification ; NOF ; normal oral fibroblast ; OSCC ; oral squamous cell carcinoma ; OTSCC ; oral tongue squamous cell carcinoma ; RIA ; radioimmunoassay ; RM ; rinsing media ; SEM ; scanning electron m
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：10 June 2016
- 年：2016
- 卷：344
- 期：2
- 页码：229-240
- 全文大小：3809 K
文摘
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Carcinoma cells do not invade into non-neoplastic tissue.
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Heart contains soluble factors that inhibit carcinoma cell migration and invasion.
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Myomas can be lyophilized and rehydrated without loss of invasion promotion.
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The use of myoma tissue in in vitro cancer studies is highly rational.