Finding the balance between over- and under-treatment of ductal carcinoma in situ (DCIS)

详细信息    查看全文

• 作者：Emma J. Groen^a ; Lotte E. Elshof^b ; Lindy L. Visser^b ; Emiel J. Th. Rutgers^c ; Hillegonda A.O. Winter-Warnars^d ; Esther H. Lips^b ; Jelle Wesseling^a ; ^b ; ^{j.wesseling@nki.nl}
• 关键词：Ductal carcinoma in situ ; Overdiagnosis ; Screening ; Risk assessment ; Quality of life
• 刊名：The Breast
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：31
• 期：Complete
• 页码：274-283
• 全文大小：452 K
• 卷排序：31

文摘

DCIS incidence is highly increased since population-based breast cancer screening. There is strong evidence that breast cancer screening results in overdiagnosis of DCIS. We are unable to predict the individual risk of DCIS progression into invasive carcinoma. Distinguishing harmless from potentially hazardous DCIS is essential to offer customized therapy in the future.