Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development
详细信息 查看全文
- 作者：Nick D.L. Owens1 ; 6 ; Ira L. Blitz2 ; 6 ; Maura A. Lane3 ; 4 ; Ilya Patrushev1 ; John D. Overton4 ; 5 ; Michael J. Gilchrist1 ; mike.gilchrist@crick.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Ken W.Y. Cho2 ; kwcho@uci.edu" class="auth_mail" title="E-mail the corresponding author ; Mustafa K. Khokha3 ; 4 ; mustafa.khokha@yale.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：26 January 2016
- 年：2016
- 卷：14
- 期：3
- 页码：632-647
- 全文大小：9188 K
文摘
- •
Ultra-high temporal resolution RNA-seq reveals smooth expression trajectories
- •
Absolute transcript measurements enable calculation of transcriptome kinetics
- •
Transcript accumulation rates vary over eight orders of magnitude during development
- •
Temporal synexpression and timescales distinguish gene functions