Recent progress on the characterization of aldonolactone oxidoreductases
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- 作者：Siddique I. Aboobuckera ; Argelia Lorencea ; b ; alorence@astate.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Aldonolactone oxidoreductase ; Ascorbate ; Galactonolactone dehydrogenase ; Gulonolactone oxidase ; Vanillyl alcohol oxidase family
- 刊名：Plant Physiology and Biochemistry
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：98
- 期：Complete
- 页码：171-185
- 全文大小：1985 K
文摘
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A flavin cofactor is a characteristic feature present in almost all aldonolactone oxidoreductases.
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An HWXK motif is present in all aldonolactone oxidoreductases for which amino acid sequences are known.
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All aldonolactone oxidoreductases that are oxidases also have dehydrogenase activity however, exclusive dehydrogenases do exist.
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Aldonolactone oxidoreductases with absolute specificity to l-galactono lactone or l-gulonolactone and promiscuous enzymes are found.
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Plants have both l-gulono-1,4-lactone oxidases and l-galactono-1,4-lactone dehydrogenases involved in ascorbate biosynthesis.