Synthesis, characterization, theoretical study and biological activities of oxovanadium (IV) complexes with 2-thiophene carboxylic acid hydrazide
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- 作者：Mudassir Jabeena ; Saqib Alib ; drsa54@yahoo.com" class="auth_mail ; Saira Shahzadia ; sairashahzadi@hotmail.com" class="auth_mail ; Saroj K. Sharmac ; Kushal Qanungoc
- 关键词：Oxovanadium (IV) complexes ; Spectroscopy ; Conductance ; Semi-empirical study ; DNA binding study ; Cyclic voltammetry ; Biological activities
- 刊名：Journal of Photochemistry and Photobiology B: Biology
- 出版年：5 July 2014
- 年：2014
- 卷：136
- 期：Complete
- 页码：34-45
- 全文大小：2488 K
文摘
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Bidentate nature of 2-thiophene carboxylic acid hydrazide.
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Thermodynamic parameters shows the stability of oxovanadium complexes.
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DNA binding study suggests the intercalative binding mode of the complexes with DNA.
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Ligand and synthesized complexes are found to be active inhibitors of urease.
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Lack of antimicrobial activity against tested bacterial and fungal strains.