Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo
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- 作者：Xiaochuan Zhanga ; 1 ; Lili Jina ; 1 ; Zhe Cuib ; Changhao Zhanga ; Xue Wuc ; Hyun Parkd ; Hongmei Quana ; lijm@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Chunmei Jina ; cmjin@ybu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Anti-Toxoplasma gondii effect ; Oxymatrine ; Matrine ; Toxicity ; In vitro and in vivo
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：165
- 期：Complete
- 页码：95-102
- 全文大小：1584 K
文摘
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OM and ME are firstly proved to have anti-Toxoplasma gondii activity in vitro and in vivo.
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Both compounds showed effective protection to the liver damage caused by T. gondii in comparison to spiramycin.
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OM and ME are likely the sources of new drugs for toxoplasmosis.