Apa2H1, the first head domain of Apa2 trimeric autotransporter adhesin, activates mouse bone marrow-derived dendritic cells and immunization with Apa2H1 protects against Actinobacillus pleuropneumoniae infection
Apa2H1 is the head domain of Apa2 trimeric autotransporter adhesin. Apa2H1 activates mouse bone marrow-derived dendritic cells. Apa2H1 vaccination triggers a mixed Th1/Th2-type immune response. Immunization of Apa2H1 protects against Actinobacillus pleuropneumoniae infection.