Gold nanostars coated with neutral and charged polyethylene glycols: A comparative study of in-vitro biocompatibility and of their interaction with SH-SY5Y neuroblastoma cells
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- 作者：Piersandro Pallavicinia ; piersandro.pallavicini@unipv.it" class="auth_mail" title="E-mail the corresponding author ; Elisa Cabrinia ; Gennara Cavallarob ; Giuseppe Chiricoc ; Maddalena Collinic ; Laura D'Alfonsoc ; Giacomo Dacarroa ; Alice Donà ; a ; Nicoletta Marchesid ; Chiara Milanesea ; Alessia Pascaled ; Laura Sironic ; Angelo Tagliettia
- 关键词：Gold nanostars ; Nanomedicine ; Biocompatibility ; Polyethylene glycol ; Endocytosis ; Two-photon luminescence
- 刊名：Journal of Inorganic Biochemistry
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：151
- 期：Complete
- 页码：123-131
- 全文大小：1462 K
文摘
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Charged or neutral polyethylene glycol coating makes gold nanostars biocompatible.
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Overcoating negatively nanostars with cationic PAH polymer promotes internalization
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Internalization of PAH-coated gold nanostars results in reduced biocompatibility.
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Two-photon luminescence allows to evidence cell internalization of gold nanostars.