Neural mechanisms of the nucleus accumbens circuit in reward and aversive learning
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- 作者：Takatoshi Hikida ; hikida@tk.med.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Makiko Morita ; Tom Macpherson
- 关键词：NAc ; nucleus accumbens ; GPi ; globus pallidus interna ; GPe ; globus pallidus externa ; VP ; ventral pallidum ; STN ; subthalamic nucleus ; SNr ; substantia nigra pars reticulate ; SNc ; substantia nigra pars compacta ; VTA ; ventral tegmental area ; MSN ; medium spiny neuron ; SP ; substance P ; Enk ; enkephalin ; MDT ; mediodorsal thalamus ; RNB ; reversible neurotransmission blocking ; D1-RNB ; D1-expressing neuron-specific RNB ; D2-RNB ; D2-expressing neuron-specific RNB ; CPP ; conditioned place preference ; LTP ; long-t
- 刊名：Neuroscience Research
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：108
- 期：Complete
- 页码：1-5
- 全文大小：631 K
文摘
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We review functional dissociation of two NAc projection neurons in learning.
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Dopamine input controls the NAc pathways via D1 and D2 receptors.
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We propose basal ganglia neural mechanisms in learning and drug addiction.