In vivo and in vitro anti-obesity activities of dihydropyranocoumarins derivatives from Peucedanum japonicum Thunb

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• 作者：Naoyuki Taira^a ; ¹ ; Ruwani N. Nugara^b ; ¹ ; Masashi Inafuku^a ; ^{h098648@eve.u-ryukyu.ac.jp} ; Kensaku Takara^c ; Takayuki Ogi^d ; Toshio Ichiba^d ; Hironori Iwasaki^a ; Takafumi Okabe^a ; Hirosuke Oku^a
• 关键词：Acaca ; acetyl-CoA carboxylase 1 ; AMD ; (+)-cis-3&prime ; -acetoxy-4&prime ; -(2-methylbutyroyloxy)-3&prime ; -4&prime ; -dihydroseselin ; BCS ; bovine calf serum ; CC ; coumarin concentrate ; Cebpa ; CCAAT-enhancer-binding protein ; alpha ; cDIVK ; cis-3&prime ; 4&prime ; -diisovalerylkhellactone ; Cpt1a ; carnitine palmitoyltransferase 1a ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; DMSO ; dimethyl sulfoxide ; Fasn ; fatty acid synthase ; FBS ; fetal bovine serum ; HFD ; high-fat diet ; HIV ; human immunodeficiency
• 刊名：Journal of Functional Foods
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：29
• 期：Complete
• 页码：19-28
• 全文大小：2297 K
• 卷排序：29

文摘

We identified two varieties of Peucedanum japonicum Thunb (PJT). Dietary coumarin concentrates from two varieties of PJT inhibited obesity. Several coumarins from PJT exhibited distinct in vitro anti-obesity activities.