Magnetic Resonance Imaging Abnormalities in Advanced Acute Bilirubin Encephalopathy Highlight Dentato-Thalamo-Cortical Pathways

详细信息    查看全文

• 作者：Jessica L. Wisnowski ; PhD¹ ; ² ; Ashok Panigrahy ; MD¹ ; Michael J. Painter ; MD³ ; Jon F. Watchko ; MD⁴ ; ^{jwatchko@mail.magee.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：kernicterus ; hyperbilirubinemia ; Rh hemolytic disease ; diffusion weighted imaging ; apparent diffusion coefficient ; cerebellum
• 刊名：The Journal of Pediatrics
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：174
• 期：Complete
• 页码：260-263
• 全文大小：740 K

文摘

A distinct pattern of acute restricted diffusion on magnetic resonance imaging localized to key regions within the dentato-thalamo-cortical pathway was observed early in a term newborn during advanced stages of acute bilirubin encephalopathy. These findings demonstrate that vulnerability to bilirubin toxicity extends across specific neuroanatomic tracts.