Differential effects of naloxone on rewarding electrical stimulation of the central nucleus of the amygdala and parabrachial complex in a place preference study
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- 作者：Antonio D.R. Agü ; era ; adrague@ugr.es" class="auth_mail" title="E-mail the corresponding author ; adaguera@motril.uned.es" class="auth_mail" title="E-mail the corresponding author ; Raquel Garcí ; a raquelgp@ugr.es" class="auth_mail" title="E-mail the corresponding author ; Amadeo Puerto apuerto@ugr.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Rewarding electrical stimulation ; Naloxone ; Parabrachial complex ; Central amygdala nucleus ; Place pReferences
- 刊名：Brain Research Bulletin
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：124
- 期：Complete
- 页码：182-189
- 全文大小：1716 K
文摘
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Electrical stimulation (ES) was used to study the brain mechanisms of reward.
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ES of central amygdala (CeA) and external lateral parabrachial nuclei induced place preferences.
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Naloxone (Nx), an opioid antagonist, blocked the rewarding effect of parabrachial ES.
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However, this antagonist failed to interrupt the rewarding ES of the amygdala.
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Distinct Nx effects support reward systems differ anatomically and neurochemically.