Inter-individual differences in pain processing investigated by functional magnetic resonance imaging of the brainstem and spinal cord
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- 作者：H.S. Khan ; P.W. Stroman ; stromanp@queensu.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：ACC ; anterior cingulate cortex ; BOLD ; blood oxygenation-level dependent ; BPN ; basilar pontine nuclei ; C8 ; 8th cervical ; fMRI ; functional magnetic resonance imaging ; FWE ; family-wise error ; GLM ; general linear model ; INS ; insular cortex ; LC ; locus coeruleus ; MIRT ; Medical Image Registration Toolbox ; mPFC ; medial prefrontal cortex ; NGc ; nucleus gigantocellularis ; NRM ; nucleus raphe magnus ; NTS ; nucleus tractus solitarius ; PAG ; periaqueductal gray matter ; PBN ; parabrachial nucleus ; PCC ; posterior c
- 刊名：Neuroscience
- 出版年：2015
- 出版时间：29 October 2015
- 年：2015
- 卷：307
- 期：Complete
- 页码：231-241
- 全文大小：1089 K
文摘
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The pain elicited by a heat stimulus varies widely across healthy participants.
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fMRI of the brainstem/spinal cord show pain-related variations across individuals.
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Structural equation modeling reveals connectivity that varies with pain ratings.
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Individual differences in pain can arise from modulation of spinal nociception.