The mechanism of regulation of ovarian maturation by red pigment concentrating hormone in the mud crab Scylla paramamosain
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文摘

A cDNA (Sp-RPCH), cloned from the mud crab Scylla paramamosain, encodes a PRCH precursor and is expressed in nervous tissues.

Sp-RPCH expression levels in nervous tissues fluctuated along a cycle of ovarian maturation.

Synthetic RPCH evoked a Ca2+ current in dissociated brain neurons.

Synthetic RPCH in vitro significantly increased mean oocyte diameter of ovarian tissues co-cultured with nervous tissues.

Synthetic RPCH in vivo significantly increased gonad-somatic index, hepatopancreas-somatic index, and vitellogenin expression in ovary and hepatopancreas.

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