Association between variation in faecal egg count for a natural mixed field-challenge of nematode parasites and TLR4 variation
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- 作者：Y.-S. Lina ; H. Zhoua ; R.H.J. Forrestb ; C.M. Framptonc ; L.E.R. Burrowsa ; J.G.H. Hickforda ; hickford@lincoln.ac.nz" class="auth_mail" title="E-mail the corresponding author
- 关键词：TLR4 ; Variation ; Gastrointestinal parasites ; Faecal egg count (FEC) ; Sheep
- 刊名：Veterinary Parasitology
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：218
- 期：Complete
- 页码：5-9
- 全文大小：364 K
文摘
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TLR4 is involved in immune responses to some helminth parasites in mammals.
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Lambs from three breeds experienced a field-challenge from gastrointestinal parasites.
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Associations were revealed between TLR4 variation and variation in faecal egg count.
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More associations were revealed when analyses were based on parasite species.
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TLR4 may thus be affecting immune response to gastrointestinal parasites in sheep.