Rising incidence of gastroschisis and exomphalos in New Zealand

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• 作者：Vijay Srivastava ; Parkash M ; han ; Kevin Pringle ; Philip Morreau ; Spencer Beasley ; Udaya Samarakkody
• 关键词：Anterior abdominal wall defects ; Gastroschisis ; Exomphalos ; Omphalocele ; Incidence
• 刊名：Journal of Pediatric Surgery
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：44
• 期：3
• 页码：551-555
• 全文大小：344 K

文摘

Background

An apparent increase in the incidence of gastroschisis and exomphalos has been reported from several parts of the world. The exact mechanism of this trend is unknown. The aim of this study was to determine the regional and national trends in the incidence of gastroschisis and exomphalos in New Zealand.

Material and Methods

This retrospective multicenter study involved collection of data from all 4 tertiary care pediatric surgical centers in New Zealand. The incidence was calculated per 10,000 live births. Data were analyzed to determine the regional and national trends. The statistical analysis was done using linear regression model and Poisson distribution.

Results

The incidence of gastroschisis has increased from 2.96 per 10,000 live births to 5.16 per 10,000 live births between 1996 and 2004. During the same period, the incidence of exomphalos has increased from 0.69 per 10,000 live births to 3.27 per 10,000 live births. Gastroschisis was observed more in younger mothers, whereas exomphalos was associated with older mothers.

Conclusion

The incidence of gastroschisis and exomphalos is increasing in New Zealand, which is consistent with worldwide trends in showing the increasing incidence of anterior abdominal wall defects.