Dementia in Parkinson's disease

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• 作者：Hasmet A. Hanagasi ; ^{hasmet@yahoo.com} ; Zeynep Tufekcioglu ; Murat Emre
• 关键词：Parkinson's disease ; Dementia ; Dementia with Lewy Bodies ; Cholinesterase inhibitors
• 刊名：Journal of the Neurological Sciences
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：374
• 期：Complete
• 页码：26-31
• 全文大小：280 K
• 卷排序：374

文摘

Parkinson's disease dementia (PDD) is a common and age-associated non-motor manifestation in patients with Parkinson’s disease. Pathologies associated with PD-D include Lewy body-type degeneration, cellular loss in subcortical nuclei and cortical Alzheimer-type pathology. Cholinesterase inhibitors such as rivastigmine and donepezil exert beneficial effects with moderate effect size.