刊名:Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
出版年:2017
出版时间:February 2017
年:2017
卷:1860
期:2
页码:184-195
全文大小:1475 K
卷排序:1860
文摘
H3K9me3 heterochromatin is robustly maintained in a dynamical manner. A new role is proposed for the accumulation of SUV39H1/2 enzymes in heterochromatin. The local concentration of SUV39H1/2 can counteract H3K9 demethylation bursts. Chromocenters are envisioned as microdomains specifying local concentrations. The concentrations of free and bound chromatin-modifying enzymes should be functionally distinguished.