- 作者：José ; Galcerá ; -Tomá ; s ; Antonio Melgarejo-Moreno ; Nuria Alonso-Ferná ; ndez ; Antonio Padilla-Serrano ; Juan Martí ; nez-Herná ; ndez ; Francisco J. Gil-Sá ; nchez ; Amparo del Rey-Carrió ; n ; José ; H. de Gea ; Pascual Rodrí ; guez-Garcí ; a ; Domingo Martí ; nez-Bañ ; o
- 关键词：Acute myocardial infarction ; Electrocardiogram ; Sex
- 刊名：Revista Española de Cardiología (English Edition)
- 出版年：2009
- 出版时间：January 2009
- 年：2009
- 卷：62
- 期：1
- 页码：23-30
- 全文大小：229 K
Introduction and objectives
In patients with acute myocardial infarction, a number of variables in the initial ECG are useful prognostic indicators. The presence of ST-segment elevation, however, usually indicates the need for reperfusion therapy. The aims of this study were to investigate sex differences in the ECGs of patients with ST-elevation myocardial infarction (STEMI) and to look for a possible association between sex and marked ST-segment elevation.Methods
A prospective observational longitudinal study of consecutive patients (n=1422) who were admitted early for a first STEMI to one of two coronary units was carried out. Initial ECG parameters were analyzed for sex differences. Multivariate analysis was performed to identify variables associated with marked ST-segment elevation (ie, total ST-segment elevation >11 mm, according to the upper tertile of the frequency distribution).
Results
In women (n=336), Q-wave myocardial infarction was observed more often in the initial ECG (19 % vs 15.6 % ; P<.03), the total ST-segment elevation was lower (10[6.6] mm vs 11.1[7.9] mm; P<.004), and marked ST-segment elevation was less common (26.4 % vs 35.5 % ; P<.005). There was an independent inverse association between female sex and marked ST-segment elevation (odds ratio=0.70; 95 % confidence interval, 0.52-0.96; P<.02).
Conclusions
In patients with STEMI, female sex was associated with a lower total ST-segment elevation and there was an independent inverse association with marked ST-segment elevation.