- 作者：Gaetana Di Fede ; Pasquale Mansueto ; Rosa Alba Longo ; GiovamBattista Rini ; Enrico Carmina
- 关键词：PCOS ; social class ; insulin ; obesity
- 刊名：Fertility and Sterility
- 出版年：2009
- 出版时间：May 2009
- 年：2009
- 卷：91
- 期：5
- 页码：1853-1856
- 全文大小：141 K
Objective
To evaluate the role of social and cultural differences inside the same ethnic group on the ovulatory status of women with polycystic ovary syndrome (PCOS).Design
To correlate social and cultural status with the phenotypic expression (body weight and ovulation) and with androgen and insulin levels of PCOS.
Setting
University department of medicine.
Patient(s)
Two hundred and forty-four consecutive PCOS women.
Intervention(s)
All studied patients completed a simple questionnaire to indicate their mean family income and their school education.
Main Outcome Measure(s)
Ovulation was assessed by measurement of serum progesterone on day 22 of a spontaneous or induced menstrual cycle. Levels of blood testosterone, sex hormone–binding globulin, insulin, and blood glucose were evaluated.
Result(s)
In the low to medium income group, 21 % of patients had ovulatory PCOS, but the prevalence of the same PCOS phenotype was 43 % in patients with high income. In patients with low education, only 12 % presented with ovulatory PCOS compared with 47 % of the patients with high education status. Mean family income negatively correlated with body mass index, waist circumference, insulin, and insulin resistance. Serum progesterone correlated negatively with insulin and insulin resistance.
Conclusion(s)
In an ethnically homogeneous PCOS population, high socioeconomic status was associated with a higher prevalence of the ovulatory phenotype. Differences in ovulatory status between the social classes seem to be related to differences in insulin levels and fat quantity and distribution.