Graft-versus-Host Disease after HLA-Matched Sibling Bone Marrow or Peripheral Blood Stem Cell Transplantation: Comparison of North American Caucasian and Japanese Populations
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- 作者：Junya Kanda1 ; Ruta Brazauskas2 ; Zhen-Huan Hu3 ; Yachiyo Kuwatsuka4 ; Koji Nagafuji5 ; Heiwa Kanamori6 ; Yoshinobu Kanda1 ; Koichi Miyamura7 ; Makoto Murata8 ; Takahiro Fukuda9 ; Hisashi Sakamaki10 ; Fumihiko Kimura11 ; Sachiko Seo12 ; Mahmoud Aljurf13 ; Ayami Yoshimi14 ; Giuseppe Milone15 ; William A. Wood16 ; Celalettin Ustun17 ; Shahrukh Hashimi18 ; Marcelo Pasquini3 ; Carmem Bonfim19 ; Jignesh Dalal20 ; Theresa Hahn21 ; Yoshiko Atsuta22 ; 23 ; y-atsuta@jdchct.or.jp" class="auth_mail" title="E-mail the corresponding author ; Wael Saber3 ; wsaber@mcw.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Graft-versus-host disease ; Bone marrow transplantation ; Peripheral blood stem cell transplantation ; Race
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：4
- 页码：744-751
- 全文大小：619 K
文摘
The impact of race on transplantation outcomes was independent of graft source.
The risk of severe acute GVHD was lower in the Japanese patients compared with the Caucasian patients.
The lower risk of acute GVHD resulted in a lower risk of nonrelapse mortality in the Japanese patients.
The risk of relapse was lower in the Japanese patients compared with the Caucasian patients.
Overall survival was higher in the Japanese patients compared with the Caucasian patients.