Clinico-pathology, hematology and biochemistry responses in buffaloes towards Pasteurella multocida type B: 2 immunogen lypopolysaccharide via oral and intravenous routes of infection
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- 作者：Eric Lim Teik Chunga ; Faez Firdaus Jesse Abdullaha ; jesseariasamy@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Hayder Hamzah Ibrahima ; b ; Ali Dhiaa Marzaa ; c ; Mohd Zamri-Saadd ; Abdul Wahid Harona ; Mohd Azmi Mohd Lilad ; Mohd Jefri Norsidina
- 关键词：Buffalo heifers ; Pasteurella multocida type B ; 2 ; Lipopolysaccharide ; Intravenous inoculation ; Oral inoculation ; Clinico-pathology ; Haematology ; Biochemistry responses
- 刊名：Microbial Pathogenesis
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：91
- 期：Complete
- 页码：141-154
- 全文大小：9970 K
文摘
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This study is a proof that oral route infection of Pasteurella multocida type B:2 immunogen lipopolysaccharide can be used to stimulate host cell responses where oral vaccine through feed could be developed in the near future.
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The clinico-pathology, hematology and biochemistry results were obtained comparing buffaloes inoculated with lipopolysaccharide via intravenous and oral route of infections and were documented for the first time.
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All buffaloes inoculated with P. multocida type B:2 immunogen lipopolysaccharide were able to survive throughout the 21 days experiment with mild clinical responses, gross and histopathology lesions.