Evidence for gene-gene epistatic interactions between susceptibility genes for Mycobacterium avium subsp. paratuberculosis infection in cattle

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• 作者：Otsanda Ruiz-Larra&ntilde ; aga^a ; ^{otsanda.ruiz@ehu.eus} ; Patricia V&aacute ; zquez^b ; ^{patriciavarbaizar@outlook.es} ; Mikel Iriondo^a ; ^{m.iriondo@ehu.eus} ; Carmen Manzano^a ; ^{carmen.manzano@ehu.eus} ; Mikel Aguirre^a ; ^{mikel.aguirre@ehu.eus} ; Joseba M. Garrido^b ; ^{jgarrido@neiker.net} ; Ramon A. Juste^b ; ^{rjuste@neiker.net} ; Andone Estonba^a
• 关键词：Cattle ; Gene interaction ; Paratuberculosis ; SNPs
• 刊名：Livestock Science
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：195
• 期：Complete
• 页码：63-66
• 全文大小：202 K
• 卷排序：195

文摘

This is the first gene-gene interaction analysis in the context of MAP infection. The identified interaction between CD209 and TLR4 could be supported by published literature. The implication of SLC11A1, NOD2, SP110, TLR2 and TLR4 in MAP infection has been replicated.