文摘
The post-natal development of Auditory Brainstem Responses (ABR) is related to functional central nervous system (CNS) maturation. In the course of a multidisciplinary study to determine the effects of early iron deficiency anemia (IDA) on CNS development, we performed ABRs in 57 Chilean 6-month-old infants, with follow-up at 12 and 18 months. Infants were classified in 3 groups according to iron status: IDA, iron deficient anemic (Hb < = 100 g/L and 2 abnormal iron measures) (n = 29); IDnA, iron deficient nonanemic (Hb = > 110 g/L and 2 abnormal iron measures) (n = 15); and nA, nonanemic good iron status (Hb = > 110 g/L and 0 or 1 abnormal iron measure) (n = 13). Infants received carefully supervised iron therapy for 6 months. ABR at 85 dB HL were recorded during spontaneous naps. Statistical analysis for differences in absolute and interpeak latencies were performed using ANOVA with sex as a covariate.