Light deprivation produces a sexual dimorphic effect on neural excitability and depression-like behavior in mice
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- 作者：Chanyi Lua ; b ; Yun Wanga ; b ; Dr. Yun-Feng Zhanga ; b ; zhangyunfeng1983@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AP ; action potential ; CLIMB ; climbing ; FST ; forced swimming test ; IMMOB ; immobility ; L5PCs ; Layer V pyramidal cells ; PAW ; pawing ; SWIM ; swimming ; TST ; tail suspension test
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：28 October 2016
- 年：2016
- 卷：633
- 期：Complete
- 页码：69-76
- 全文大小：976 K
文摘
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Light deprivation produces a sexual dimorphic effect on depression-like behavior.
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Light deprivation induces more severe depressive-like symptoms in female mice.
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Light deprivation leads to weaker locomotor activity in female depressive-like mice.
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Light deprivation leads to lower excitability of L5PCs in female depressive-like mice.
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Lower excitability of L5PCs may correlate with more severe depressive-like symptoms.