Effects of combined high pressure and thermal treatment on the allergenic potential of peanut in a mouse model of allergy
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- 作者：Fangyu Longa ; 1 ; Xin Yangb ; 1 ; Jiao Sunc ; Qinyue Zhonga ; Jianping Weia ; Pu Qua ; Tianli Yuea ; yuetl@nwafu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：ELISA ; enzyme-linked immunosorbent assay ; HHP ; high hydrostatic pressure ; IFN ; interferon ; IG ; intragastric ; IL ; interleukin ; PBS ; phosphate-buffered saline ; PCR ; polymerase chain reaction ; SD ; standard deviation ; SPT ; skin prick test ; PN ; Ara h 2 in peanut ; PNH ; high-pressure and heat-treated Ara h 2 ; CT ; cholera toxin ; mRNA ; messenger ribonucleic acid ; IgE ; immunoglobulin E
- 刊名：Innovative Food Science & Emerging Technologies
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：133-138
- 全文大小：988 K
文摘
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Ara h 2 is the major allergen in peanut.
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We analyzed the allergenicity of Ara h 2 in peanut (PN) after pressure and heat treatment.
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Reduced IgE-binding with PN was observed following pressure and heat treatment.
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Decreased PN-specific IgE titers were observed in mice fed treated PN.
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The allergenicity of PN was abolished following pressure and heat treatment.