PBMCs express MMP8 and MMP9 which are inducible by the S100A8 and S100A9.
MMP9 expression reflects the presence of PDAC-associated diabetes mellitus.
PDAC-derived PBMCs express high MMP8 and low S100A9 transcript levels.
The expression of S100A9, not those of MMPs, are of prognostic relevance in PDAC.